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Dicerna Inc drug dcr myc
Drug Dcr Myc, supplied by Dicerna Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/drug+dcr+myc/101+6+based+dcr+lipid+myc+nct00882180+np+phxc/pmc13150417-177-2-6
Average 86 stars, based on 1 article reviews
drug dcr myc - by Bioz Stars, 2026-11
86/100 stars

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Allele-specific Oligonucleotide:

Article Title: Oncogene c-Myc: From molecular mechanism to targeted therapy (Review)
Article Snippet: .. The representative drug DCR-MYC (developed by Dicerna, using the proprietary GalXC TM delivery technology) is an intravenous siRNA designed to specifically silence MYC mRNA; antisense oligonucleotides (ASO) are single-stranded DNA/RNA molecules that mainly inhibit translation through RNase H-mediated mRNA degradation or steric hindrance. .. Although AZD4785 (developed by Ionis/AstraZeneca, targeting KRAS mRNA) does not directly act on c-Myc, its clinical success strongly validates the feasibility of ASO technology in targeting ‘undruggable’ oncogenic transcripts.



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